The environmental conditions (stress, pesticides), individual genotype (genomic and mitochondrial DNA) and stochastic factors can induce genetic and epigenetic alterations that cause a decline in somatic stem cell function that can be the origin of metabolic, degenerative diseases, cancer and aging in the individuals.
What are environmental and genetic factors?
Your genes hold the basic instructions for your body to grow and function, but they are far from the only thing controlling your traits. Most traits are shaped both by a person’s genes and by environmental factors. Environmental factors include everything outside of DNA that affects your traits.
What are some environmental factors that can affect aging?
The most notable exogenous factors influencing degree of aging were sun exposure and smoking. Other possibly contributory lifestyle factors include alcohol consumption, stress, diet, exercise, disease, and medication.
What are 5 examples of genetic factors?
- Familial Alzheimer’s Disease.
- Familial FTD.
- Familial Prion Disease.
- Genetic Counseling.
How does genetic affect aging?
Genes that promote ageing include some that encode yolk proteins, consistent with a link between ageing and reproduction. Another pro-ageing protein is the insulin-like INS-7, which, by binding to the insulin/IGF-1 receptor (DAF-2), may repress DAF-16 on the same and other cells.
What are the 5 environmental factors?
Environmental factors include temperature, food, pollutants, population density, sound, light, and parasites.
How environmental factors affect genes?
Environmentally induced changes in gene expression occur when exposure to chemicals changes which genes are turned “on” or “off”—which can change how the cells function and thus a person’s predisposition to disease. The effect of this chemical modification is called epigenetic regulation.
What is environmental aging?
Older adults face increased risks from exposure to environmental health contaminants. … Environmental pollutants and chemicals adversely influence the homeostatic status of aging, frequently resulting in development of certain diseases at an earlier age than expected.”
Is age a genetic factor?
It is estimated that about 25 percent of the variation in human life span is determined by genetics, but which genes, and how they contribute to longevity, are not well understood. … Scientists speculate that for the first seven or eight decades, lifestyle is a stronger determinant of health and life span than genetics.
What are the major causes of aging?
The Causes of Aging
- Collagen breakdown. Represents 75% of the skin’s dry weight. …
- Photo Defence. Repeated exposure to ultraviolet light (UV radiation) from the sun accounts for almost 90% of symptoms of premature skin ageing, skin damage and skin cancer. …
- Oxidation. …
- Inflammation. …
What are example of genetic factors?
Genetic variations can have large or small effects on the likelihood of developing a particular disease. For example, certain variants (also called mutations) in the BRCA1 or BRCA2 genes greatly increase a person’s risk of developing breast cancer and ovarian cancer.
What are some examples of genetics?
Our genes carry information that gets passed from one generation to the next. For example, genes are why one child has blonde hair like their mother, while their sibling has brown hair like their father. Genes also determine why some illnesses run in families and whether babies will be male or female.
What do you mean by genetic factors?
In many diseases genetic factors are important. This means that part, or all of the risk, is passed down from one’s parents. Certain diseases are caused by an abnormality in one single gene and CADASIL is one of these diseases. Genes produce proteins which are necessary for normal functioning of the body.
What environmental and genetic conditions might play a role in a person’s tendency to contact a disease?
What environmental conditions might play a role in a person’s tendency to contract a disease? (Answers may vary and could include: air pollution, water pollution, pesticides, chemicals, and radiation.) Genetics too can play a role in a person’s tendency to contract a certain disease.
Do you believe aging has one single cause or is it a combination of environmental factors and genetics?
A person’s life span is thought to be largely determined by the combined effects of genetics and environmental factors. Twin studies, however, suggest genetics only account for approximately 20 to 30 percent of an individual’s chance of surviving to age 85.